Coming from Chicago, I am a harsh critic of Italian restaurants. So, after trying a few others here in Fort Wayne, I was very surprised to come across Casa D'Angelo's. I have been there over 5 times already and their food is fantastic! The restaurant has a great older Italian atmosphere (not to mention it is in a actual neighborhood - not a strip mall), the service is great and the prices are very reasonable. They also have a good wine selection.
For anyone looking for a good Italian meal in Fort Wayne, this would be my very first recommendation!